IVF preparation
IVF Optimisation · Sessions 1–5

IVF Prep

Timeline

Your 90-day roadmap to egg retrieval or embryo transfer. Each phase reveals the nutritional, supplemental, and lifestyle priorities for that specific biological window.

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90 days
the egg quality window before retrieval
74 days
sperm maturation cycle — partner prep matters too
improvement in blastocyst rate with CoQ10 supplementation
8 mm
minimum endometrial thickness for transfer
01

Why the 90-Day Window Changes Everything

The oocyte you will retrieve at egg collection has been in its final growth phase for approximately 90 days. During this window — called folliculogenesis — the egg is exquisitely sensitive to its nutritional and metabolic environment.

Mitochondrial density, oxidative stress levels, intra-follicular antioxidant status, and insulin sensitivity all directly influence whether that oocyte will fertilise, divide normally, and reach blastocyst stage. These are modifiable factors — which means your choices in the next 90 days have measurable clinical impact.

Improves oocyte mitochondrial function
Reduces aneuploidy risk
Supports blastocyst development
Optimises endometrial receptivity
Reduces OHSS risk
Supports luteal phase implantation

The Biological Timeline

Day 90
Primordial follicle recruited into growth pool
Day 60
Follicle enters antral phase — granulosa cells multiply
Day 30
Dominant follicle selection begins
Day 14
Stimulation injections begin
Day 0
Egg retrieval
02

Your 90-Day Phase Explorer

Select a phase to explore the targeted priorities, supplements, and nutrition for that specific biological window.

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Laying the Cellular Foundation

Day 90–61

The oocyte you will retrieve in 90 days is already in its final growth phase. The decisions you make now — nutrition, supplementation, sleep, and stress — directly shape the mitochondrial energy capacity of that egg.

Key Focus Areas

  • Optimise mitochondrial function with CoQ10 (ubiquinol form, 400–600 mg/day)
  • Establish anti-inflammatory dietary baseline: Mediterranean-style, low glycaemic
  • Begin or consolidate prenatal folate (methylfolate preferred over folic acid)
  • Reduce alcohol to zero — ethanol impairs oocyte spindle assembly
  • Identify and remove endocrine-disrupting chemicals from home environment
  • Establish consistent sleep schedule — 7–9 hours, lights out by 10:30 pm

Supplement Protocol

  • CoQ10 (ubiquinol) 400–600 mg
  • Methylfolate 400–800 mcg
  • Vitamin D3 (check levels first)
  • Omega-3 DHA/EPA 2 g/day
  • N-Acetyl Cysteine 600 mg

Nutrition Priorities

  • Prioritise colourful vegetables at every meal
  • Include oily fish 3× per week (sardines, salmon, mackerel)
  • Reduce ultra-processed foods and refined carbohydrates
  • Adequate protein: 1.2–1.6 g/kg body weight daily

Tell Your Practitioner

  • !Ongoing alcohol consumption
  • !BMI outside 18.5–30 range — discuss with practitioner
  • !Unmanaged thyroid dysfunction
  • !Untreated vitamin D deficiency (<75 nmol/L)
03

Retrieval & Transfer Protocol

The 48 hours surrounding retrieval and transfer are the highest-leverage windows in your IVF cycle. Here is exactly what to do and when.

Egg Retrieval

48h before

Final Preparation

  • Pause vitamin C and high-dose antioxidants
  • Increase protein and electrolytes
  • Acupuncture session if available
  • Light walking only — no gym
Day of retrieval

Retrieval Day

  • Fast as instructed by clinic (usually from midnight)
  • Acupuncture 1–2h before procedure if available
  • Wear loose, comfortable clothing
  • Arrange transport — you cannot drive after sedation
24–48h after

Immediate Recovery

  • Rest completely — no exercise
  • High protein diet to support recovery
  • Electrolytes to reduce OHSS risk
  • Monitor for OHSS symptoms: bloating, pain, reduced urination
Day 3–5

Fertilisation Updates

  • Clinic will call with fertilisation report (Day 1)
  • Day 3 or Day 5 biopsy/blast check
  • Continue supplements as directed
  • Manage anxiety — most embryos arrest between Day 3–5 (normal)

Embryo Transfer

5–7 days before

Endometrial Prep

  • Confirm lining thickness at scan (target ≥8 mm, trilaminar pattern)
  • Acupuncture to support uterine blood flow
  • Warm foods, avoid cold drinks and raw foods
  • Reduce stress — cortisol impairs endometrial receptivity
Day of transfer

Transfer Day

  • Acupuncture 1h before and 1h after transfer if possible
  • Arrive with a comfortably full bladder (clinic will advise)
  • Wear warm, loose clothing
  • Plan for a gentle, restful day after
Transfer → test day

The Two-Week Wait

  • Continue all prescribed medications exactly as directed
  • Gentle walking only — no high-intensity exercise
  • Prioritise sleep and stress regulation
  • Avoid pregnancy tests before clinic-advised date
04

Luteal Phase & Implantation Support

The two-week wait is not passive. The endometrial environment you have built over 90 days is now the stage for implantation. These are the evidence-based priorities for this window.

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Progesterone Support

Your clinic will prescribe progesterone supplementation (pessaries, injections, or gel). This is non-negotiable — do not skip doses. Progesterone maintains the endometrial lining and suppresses immune rejection of the embryo.

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Nutritional Support

Continue high protein, anti-inflammatory diet. Prioritise vitamin B6 (supports corpus luteum function), magnesium (reduces uterine contractility), and zinc (essential for early embryonic cell division).

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Nervous System Regulation

HPA axis activation elevates cortisol, which competes with progesterone receptors and suppresses uterine natural killer cell tolerance. Daily parasympathetic activation — breathwork, gentle yoga, nature walks — is clinically meaningful.

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Sleep Prioritisation

Melatonin produced during deep sleep acts as an antioxidant in the developing embryo's microenvironment. Consistent sleep timing (same bedtime nightly) stabilises the circadian hormone cascade that supports early implantation.

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Temperature Awareness

Avoid saunas, hot baths, and hot yoga during the luteal phase and two-week wait. Core temperature elevation above 38.5°C impairs early embryonic development and can disrupt implantation.

IVF Prep Timeline — Quick Reference
One-page PDF cheat sheet · Supplement doses, food priorities & action steps
Download PDF
05

Your IVF Action Plan

Tick each item as you complete it. Bring this checklist to your coaching sessions — your practitioner will review your progress at each milestone.

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Foundation (Day 90–61)

Start CoQ10 (ubiquinol) 400–600 mg daily
Begin methylfolate 400–800 mcg daily
Remove alcohol completely
Complete Detox Audit and remove EDCs from home
Establish consistent sleep schedule (lights out by 10:30 pm)

Optimisation (Day 60–31)

Add myo-inositol 2–4 g/day
Add melatonin 3 mg at night
Confirm baseline bloods reviewed with practitioner
Begin weekly acupuncture
Establish daily stress regulation practice

Pre-Stimulation (Day 30–15)

Confirm all supplements at therapeutic dose
Attend baseline scan and Day 2–3 bloods
Increase hydration to 2–2.5 L/day
Reduce exercise to moderate intensity

Stimulation Phase

Maintain high protein intake throughout stimulation
Add daily electrolytes
Attend all monitoring scans
Book acupuncture for day before and day of retrieval

Retrieval & Transfer

Pause vitamin C 48h before retrieval
Arrange transport for retrieval day
Book acupuncture around transfer date

Luteal Phase

Take all prescribed progesterone without skipping doses
Continue anti-inflammatory diet throughout two-week wait
Avoid saunas, hot baths, and hot yoga